| Dimethyl Glycine | ||||||||
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- Why dimethyl glycine is good for you
- Important dimethyl glycine facts
- Groups at risk of dimethyl glycine deficiency
- Symptoms of dimethyl glycine deficiency
- Dimethyl glycine and health
- Dimethyl glycine in foods
- How to take dimethyl glycine
- Dimethyl glycine works best with
- Overdosage, toxicity and cautions for dimethyl glycine
Why dimethyl glycine is good for you
Dimethyl glycine is produced in cells as a mid-way in the metabolism of choline to glycine. It acts as a building block for the biosynthesis of many important substances such as methionine, choline, several important hormones, neurotransmitters, and DNA.
This means dimethyl glycine supports mental activity, aids to enable high energy levels, enables a strong immune system, improves oxygen utilization, and improves the functioning of many important organs.
Dimethyl glycine is naturally produced in small amounts in the body.
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Important dimethyl glycine facts
- Dimethyl glycine is considered a food
- Dimethyl glycine (DMG) is a derivative of glycine
- Dimethyl glycine (DMG) is sometimes referred to as Vitamin B15
- Another name for dimethyl glycine (DMG) is pangamic acid
- It has not yet been determined whether dimethyl glycine (DMG) is a vitamin
- DMG is absorbed from the small intestine and it is then transported to the liver. DMG is metabolised in the liver where it is converted to glycine
- DMG itself is formed from trimethylglycine or betaine. DMG that is not metabolised in the liver is transported to various areas in the body
Groups at risk of dimethyl glycine deficiency
- People taking certain medications - certain prescription drugs can interfere with or block dimethyl glycine absorption, so supplementation may be required
- Alcoholics - alcoholics tend to eat poorly, so their vitamin intake is low and alcohol blocks absorption of many nutrients, as well as excreting much of it that is absorbed
- People with degenerative illnesses - people with degenerative illness such as diabetes may not be absorbing a lot of their vitamins and minerals, or may be excreting them too quickly, so may require supplementation
- People with cardiac problems - may need extra dimethyl glycine
- People who drink a lot of coffee - coffee blocks absorption of dimethyl glycine
Talk to a medical professional about essential fatty acids supplements BEFORE taking them
Symptoms of dimethyl glycine deficiency
No dimethyl glycine deficiency symptoms have been reported in the general population, so it is generally assumed that normal absorption and a varied diet provides sufficient coenzyme Q10 for healthy individuals. The only individuals that may be at risk of deficiency are those in the groups above. |
- Immune function - a study on animal subjects demonstrated that the immune systems of the animals that were given dimethyl glycine showed 300% to 1,000% better response to infection than the controls. In a double blind human study, DMG enhanced immune responses by stimulating white blood cell metabolism
- Maintain high energy levels and boosting mental alertness - research shows that dimethyl glycine helps to boost mental activity and energy levels as it increases blood and oxygen supply to the brain and other tissues, as well as boosting energy metabolism
Talk to a medical professional about dimethyl glycine supplements BEFORE taking them
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Foods high in dimethyl glycine are:
- Apricot kernels
- Brewer's yeast
- Pumpkin seeds
- Sunflower seeds
- Whole grains such as brown rice
As dimethyl glycine is a derivative of glycine, it can be found in foods high in glycine.
Dosage of dimethyl glycine depends on the condition that is being treated. A medical doctor and/or alternative health care provider can advise on individual cases - this information is provided as a guide only:
| lifestage | age | Amount (per day) |
|---|---|---|
| INFANTS | 0-12mths | Not recommended - seek medical advice |
| CHILDREN | 1-8yrs | Seek medical advice before taking it |
| CHILDREN | 9-18yrs |
Seek medical advice before taking it |
| ADULTS | 19-50yrs |
General Health & Immune Support 50mg twice a day |
| SENIORS | 51+yrs | General Health & Immune Support 50mg twice a day |
| PREGNANT | Seek medical advice before taking it | |
| LACTATING | Seek medical advice before taking it |
People who wish to take an dimethyl glycine supplement should talk to a medical professional BEFORE taking it.
Dimethyl glycine works best with
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Overdosage, toxicity and cautions for dimethyl glycine
Not a great deal of evidence has been seen of any toxic or significant adverse effects of taking high levels of DMG.
The only known side effects of overdosage are:
- drowsiness
- mild flushing of the skin
references
- Balch, J. & Balch, P. Prescription for Nutritional Healing. New York: Avery Publishing Group, 2000
- Bolman WM, Richmond JA. A Double-Blind, Placebo-Controlled, Crossover Pilot Trial of Low Dose Dimethylglycine in Patients with Autistic Disorder. Journal of Autism and Development Disorders 1999. 29 (3); 191-194
- Lawson, J. & Reap, E. “The effects of dimethylglycine on the immune response of rabbits.” Clemson University Presented at the American Society of Microbiologists. Abstract, March 1-6, 1987, Atlanta, Georgia
- McGregor DA etc al. Dimethylglycine accumulates in uremia and predicts elevated plasma homocysteine concentrations. Kidney International (2001) 59, 2267–2272;
- Santarsiero BD, Marsh RE. N,N-Dimethylglycine hydrochloride. Journal of Chemical Crystallography 1983. 13 (4); 245-251
- Schneider D; Helwig V; Staniek K; Nohl H; Elstner EF. Studies on the chemical identity and biological functions of pangamic acid. Arzneimittelforschung, 1999. Apr, 49 (4); 335-43
