| Intrinsic factor | |||||
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Intrinsic factor is a glycoprotein which is secreted by parietal cells of the mucous membranes of the stomach.
Intrinsic factor has an important role in the absorption of vitamin B12 (cobalamin) in the intestine.
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Important intrinsic factor facts
- Intrinsic factor helps to absorb the vitamin B12 (cobalamin) in food
- People with a lack of intrinsic factor need to get injections of vitamin B12 (cobalamin) to prevent pernicious anaemia
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Why intrinsic factor is important
Intrinsic factor is an important protein in the body. If not enough intrinsic factor is produced or it is not used properly, it can result in the condition called pernicious anaemia , which is a type of anaemia caused by a failure to absorb vitamin B12 (cobalamin).
Lack of intrinsic factor can also cause a deficiency of vitamin B12 (cobalamin), which can lead to all sorts of health problems.
references
- Marieb EM, Hoehn K. Human Anatomy & Physiology. 7th edition, 2006. Benjamin Cummings Publishing
- Osiecki, Henry, The Nutrient Bible 2002, BioConcepts Publishing
- Osiecki, Henry. The Physician's Handbook of Clinical Nutrition. 6th edition, 2001, BioConcepts Publishing
- Tortora GJ, Derrickson BH. Principles of Anatomy & Physiology. 11th edition, 2005. Wiley Publishing
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